Throughout history, bacteria have caused countless fatal diseases. Yet, in recent decades, antibiotics revolutionized treatment. However, bacteria's rapid evolution, fueled by large populations and widespread antibiotic use, leads to alarming resistance, with no antibiotic being spared. We may be facing a dangerous post-antibiotic era where once-treatable diseases threaten lives again.

Though less publicized than bacterial diseases, fungal infections (mycoses) are a major threat, especially fatal to immunocompromised individuals. In addition, mycoses are especially common in plants,  affecting farm production worldwide, causing mass devastation of crops and threatening food security. 

However, resistance to many fungicides has already emerged and spread in pathogen populations. Moreover, the time to resistance evolution has been shown to decrease: the later the drug was introduced, the shorter the time until the resistance was recorded.